However, they are difficult to be used in the clinic due to many side effects.The effect of antagonist or agonist of mGluR on spilepsy is being studied.

• 离子型谷氨酸受体拮抗剂可明显抑制多种致痫剂诱导的抽搐，但由于其较多的副作用而未能应用于临床。