Histone deacetylase (HDAC) greatly affects the chromatin topology and gene expression,and HDAC can be a new strategy in human cancer or tumour therapy.

• 组蛋白去乙酰化酶(HDAC)对染色质分布和基因调节起着重要的作用,也是治疗癌症和其它疾病的新靶点。