High glucose promote the maturation of MDCs and augment their capacity to stimulate T-cell proliferation and cytokine secretions at least in part through enhancing intracellular ROS generation.

• 高糖显著增强树突状细胞内ROS,从而促进树突状细胞成熟,激活T淋巴细胞的能力也明显增强,并且通过促进树突状细胞本身释放一些炎症因子,加速和放大炎症免疫反应。