Hamster cardiac xenografts survival time have a significant correlation with rat serum IgM. EXA, ERL and RAD together or in combination with CyA can effectively inhibit the IgM immune response and therefore significantly prolong xenografts survival time.

• 仓鼠移植物存活时间与受体血清IgM型诱生抗体水平呈显著的负相关 ,ERL、RAD与CyA配合使用能有效抑制大鼠抗仓鼠IgM并明显延长异种移植物的存活时间。