HER-2/neu might be a useful target of immunotherapy in gastric carcinoma. Anti-HER2+anti-CD3 BsAb is of in vitro and in vivo antitumor effect.

• HER-2/neu是胃癌免疫治疗的有效靶点,基因工程抗HER-2+抗CD3 BsAb在体外及体内均具有有效的抗肿瘤活性。