General research can only reach the detection limit of 106 cfu/ml. Medina et al used SPR-immunochemical methods to detect E. Coli O157:H7.The direct detection of bacteria cells provided low responses.

• Coli O157:H7 和沙门氏菌,扩展了表面等离子体共振(SPR)生物传感器对微生物的检测限,并实现了快速检测。