From the development of medical image registration method through the world,we find that principal axes and centroid based method has many good points to coarse match in combine registration method.

• 根据当前国内外医学图像配准技术的发展现状,发现主轴质心法作为混合配准算法中的粗匹配算法,具有速度快、鲁棒性相对较高,易实现等优点。