From each COG, researcher can determine the conserved amino acid and the evolution of the protein, and also can extrapolate the protein function according to the protein of the same COG.

• 通过同源蛋白质簇，可以被用来确定保守序列残基和分析成员蛋白质的进化关系，并可通过已知蛋白质来推断未知蛋白质的功能。