Four patients who received lamivudine monotherapy developed decompensation with elevated serum bilirubin from 52 IU/1 to 153 IU/1 at week 12 to 22 post -treatment.

• 4例拉米夫定治疗患者出现失代偿,治疗后从12到22周血清胆红素从52 IU/l升至153 IU/l。