Four patients (7%) discontinued the agent due to adverse events.Of the patients also receiving nephrotoxic immunosuppressant drugs, 84% had normal serum creatinine levels or only grade 1 elevations.

• 在同时使用具肾脏毒性的免疫抑制药物者之中，有84%25 的血清肌酸酐是正常的、或者仅是等级1的增加。