Families who fit Amsterdam criteria are called ICG-HNPCC, while others who fit suspected HNPCC criteria are named as sHNPCC. It has been reported that ICG-HNPCC and sHNPCC families shared similar clinicopathological and molecular characteristics.

• HNPCC呈常染色体遗传，具有独特的临床、病理特征，符合Amsterdam诊断标准称为ICG-HNPCC，符合可疑HNPCC(Suspected HNPCC，sHNPCC)诊断标准的称为sHNPCC，已有研究证明两者具有相似的分子基础。