Etodolac was synthesized with 7-ethyltryptophol and methyl 3-oxopentanoate as the starting materials.Highly pure etodolac was obtained by purifying the crude product with a mixing solvent.

• 以7-乙基色醇和3-氧代戊酸甲酯为起始原料；以甲醇为溶剂；合成了依托度酸.；采用混合溶剂对粗品进行精制；得到了高纯度的依托度酸