Escape of renin from suppression by excess aldosterone is associated with eidence of more seere renal damage in patients with primary aldosteronism and predicts less faorable outcomes after treatment.

• 大量醛固酮会抑制肾素分泌，为降低其损害，有证据表明，原发性醛固酮增多症患者伴有更严重的肾损害，预期治疗效果不佳。