Epidermal explant culture was applied, and effects of AK auto Ab with variable dose on rate of epidermaration were observed. Brd U incorporation assay was used to investigate the extent of mitosis.

• 方法 采用贴壁法体外培养皮肤 ；比较观察不同浓度 AK auto Ab对表皮形成速率的影响 ；并采用 Brd- U掺入法测定各组细胞增殖率 .