Endostatin, a 20 kD C-terminal fragment of collagen XVIII, is a potent inhibitor of angiogenesis and tumor growth without acquired drug resistance in animal models.

• Endostatin (血管内皮抑素) 是一个20 kDa 的蛋白质,能有效阻止肿瘤血管生成,动物模型试验也表明endostatin能有效地抑制小鼠多种移植肿瘤生长,且无任何毒性。