Employing diversity-oriented synthesis (DOS) to construct skeletally complex natural product-like libraries and using it in the studies of chemical biology and lead discovery is becoming a tendency.

• 用多样性导向合成方法建立骨架多样、构造复杂、立体化学多样性的“类天然产物”化合物库进行生物学相关研究，并以此为基础发现药物先导化合物正在成为一种趋势。