Elevated serum IgE antibody, manifested symptoms of nasal hypersensitivity and imme-diate release of histamine in nasal secretions after nasal antigen challenge in guinea pigs are similar to the manifestations of nasal allergy in humans.

• 在过敏化过程中亦有呼吸道敏的现象，显示此实验模式可以模拟人类的呼吸道过敏症。