Early in 1952, Fatt and Katz first recorded spontaneous miniature end-plate potentials(MEPP) in frog NMJ, and showed that they were the result of spontaneous release of transmitter substance, acetylcholine (ACh), from motor nerve terminals.

• 1952年，Fatt和Katz首先在蛙NMJ记录到自发性小终板电位(MEPP)，并证明它是运动神经末梢自发释放递质性乙酰胆碱(ACh)的结果。