EGb761 could ease ischemic cerebral injury of rats andone of its protective role may be realized by inhibiting the activies of Caspase-9 and Caspase-3,having a relationship between does and effect.

• EGb761能够减轻大鼠缺血性脑损伤,实现保护作用的机制可能是通过降低Cas-pase-9、Caspase-3活性实现的,并且疗效与剂量有关。