Due to the long poly A repeat units in exon 7 and 8 of PTEN, we supposed that PTEN can be the target gene of MSI, Our purpose was to investigate the relationship between PTEN and MSI.

• 由于PTEN第7，第8外显子的编码序列存在(A)6重复单位，它可作为MSI作用的靶位点，本项研究将会探讨胃癌中PTEN基因突变与MSI的关系，从而明确PTEN可否作为MSI作用的靶基因。