Domestic disaster looms for male nurse Greg Focker (Stiller) when his straight-laced, ex-CIA father-in-law (De Niro) asks to meet his wildly unconventional mum and dad (Streisand and Hoffman).

• 经过千辛万苦，男护士阿基（宾史迪拿饰）才获得前CIA探员外父（罗拔迪尼路饰）首肯，让女儿下嫁自己。