Disadvantages of using etomidate include a high incidence of postoperative nausea and vomiting (decreased with prophylaxis with an antiemetic drug) and a postoperative suppression of adrenocortical function seen with infusion of this sedative-hypnotic.

• 缺点是术后恶心、呕吐（预防性的应用镇吐剂可减少发生）术后肾上腺皮质功能减退。