Direct ligation of fluconazole to the heme iron is obsered in a minority of CYP121 molecules, albeit with seere deiations from ideal geometry due to close contacts with actie site residues.

• 氟康唑直接与亚铁血红素铁原子直接配合在少数CYP121分子中也可以观察到，由于紧密的与活性位点残基作用，严重的背离了理想的几何形状。