Demyelination in brain tissues and lymphocyte depletion are main factors that cause dogs suffering from canine distemper, but the mechanism of lesions is unclear now.

• 脑组织中髓鞘脱失和淋巴组织中淋巴细胞减少是犬瘟热发生的主要原因,但其发生的机理还未完全搞清。