Corticotropin-relaesing factor,as a kind of nervous-incretion-peptide related to stress,harmonizes the autonomic,endocrine,immunological and behavioral response to stress through G-protein coupled receptors,CRF receptors-type 1 and type 2.

• 促肾上腺皮质激素释放因子(corticotrop in-releasing factor,CRF)是一种与应激密切相关的神经内分泌肽,通过与G蛋白偶联的2种受体结合发挥整合、协调内分泌、自主神经系统、免疫系统及行为学各方面对应激的反应。