Constractions of intralobular arteriolar sphincter, pres ence of vacuoles in all the layers of sphincter, grossirregularity in capillary network of acini were observed in caerulein-induced groups.

• 光镜及扫描电镜显示胰腺小叶内动脉括约肌早期出现损伤，细胞胞浆内大量空泡形成，表现为持续痉挛，所属微动脉支配区域毛细血管床构形紊乱；