Conclusions. Chinese herbs could significantly reduce the level of COX-2 and IL-8 in synovium of MSU induced rabbit actue arthritis and had better preventing and curing effect.

• 表明自拟方剂能够显著抑制急性痛风性膝关节炎家兔模型滑膜组织IL-8和COX-2mRNA的表达,对急性痛风性关节炎具有较好的防治作用。