Conclusions:The hair colour cosmetics of 50% and 100% density can induce irreversible patho-damage in skin Malpighian cell and dermis fibroblast and inhibit the growth of guinea pig and so on.

• 结论：50%25、100%25浓度的染发剂可导致豚鼠皮肤角质形成细胞和成纤维细胞发生不可逆病理改变，以及豚鼠的生长抑制等全身性影响。