Conclusions: Taurine had prot ective role agai nst ethanol induced gastric mucosal injury and its mechanism might related to t he regulations release and contents of ET, GMBF and GMPD.

• 结论:牛磺酸可明显减轻胃粘膜损伤，其机制可能与调节胃粘膜局部ET，GMBF和GMPD有关。