Conclusions: Quantified intragastric administration of 2% DSS can induce stably acute colitis similar to human UC in mice with a high homogenicity and low mortality rate.

• 结论：2%25DSS定量灌胃诱导的小鼠急性结肠炎模型能较稳定地模拟人类UC，均一性高，动物死亡率低。