Conclusions There were no gene mutations of SCN1B in the probands of 6 GEFS(superscript +) families.GEFS(superscript +) is a complex disorder with genetic heterogeneity.

• 结论全面性癫癎伴热性惊厥附加症是一种复杂综合征，本组家系中未发现SCN1B基因突变，GEFS(上标+)具有遗传异质性。