Conclusions Peripancreatic region perfusion with 1%lidocaine and systemic application of anisodamine may be effectively preventing the exacerbation of ANP and providing a new feasible approach to ANP.

• 结论腹腔胰腺周围灌注1%25利多卡因，同时应用山莨菪碱，能有效阻止ANP进展恶化，为临床综合治疗ANP提供了一条可能的药物治疗新途径。