Conclusions Marked changes of MAP2-IR are found in hippocampal dentate gyms after PTZ induced seizure, while Diazepam used after seizure has no notable effect on MAP2-IR change.

• 结论致癎大鼠海马齿状回MAP2-IR变化显著，癎后的地西泮干预不能改变MAP2-IR的变化规律。