Conclusion:PAI-1 ,upar and vitronectin are not normally expressed in lupus nephritis kidneys but are commonly up-regulated in lupus nephritis kidneys.
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结论:在狼疮肾病肾穿刺组织中PAI-1和vitronectin表达上调,与基质增生和慢性化程度呈正相关,且PAI-1,vitronectin在同一部位共表达,提示PAI-1通过和vitronectin结合参与肾脏纤维化过程。