Conclusion:PAI-1 ,upar and vitronectin are not normally expressed in lupus nephritis kidneys but are commonly up-regulated in lupus nephritis kidneys.

• 结论:在狼疮肾病肾穿刺组织中PAI-1和vitronectin表达上调，与基质增生和慢性化程度呈正相关，且PAI-1,vitronectin在同一部位共表达，提示PAI-1通过和vitronectin结合参与肾脏纤维化过程。