Conclusion: MMP-9 is overexpressed in the brain of mice with Cryptococcal meningitis;MMP-9 might lead to increased permeability of blood brain barrier.

• 结论:隐球菌性脑膜炎小鼠脑组织中存在MMP-9过表达,MMP-9可能导致血脑屏障开放程度提高。