Conclusion: Fluorine can reduce the cariogenic effects in desalivated mice, but Zinc, Boron, Barium, Manganese have the antagonism to Fluorine.

• 结论：一定浓度氟具有明显抑龋作用，过量的锌、硼、钡、锰对氟的抑龋作用有拮抗，增加龋病的发生率。