Conclusion Podophyllotoxin delivered via solid lipid nanoparticle gel can effectively clear condyloma acuminatum and reduce its recurrence rate with only mild, tolerable adverse effect.

• 结论鬼臼毒素脂质纳米粒凝胶局部外用不良反应轻微，耐受性好，并能降低尖锐湿疣复发率。