Comparing the nr database with the IPI database by using NCBI blastp program to align human protein sequences,this paper provides an evidence of necessity of integrating the nr database in the protein annotation system.

• 通过用NCBI的blastp程序对nr数据库与IPI数据库中属于人类的蛋白质序列进行比较,论证了nr数据库整合到蛋白质注释系统中的必要性。