Compared with 4-ASA non-coated tablet group,decreased macroscopic and histo- logical damage score and lower MPO activity were observed after the oral administration of 4-ASA coated tablets or SASP.

• 与4-ASA非包衣片组相比,包衣片组或SASP组显示,给药后动物结肠的大体形态改变评分、组织损伤评分及MPO活性均有所降低；