Collagenase at the therapeutic concentration applied in clinical CCN has no remarkable effects on NCV of rat spinal nerve,and to a certain extent, percutaneous intervertebral disc CCN is relatively reliable.

• 临床应用于经皮椎间盘胶原酶化学髓核溶解术治疗浓度的胶原酶对大鼠脊神经传导速度未产生明显的影响,经皮椎间盘胶原酶化学髓核溶解术这项治疗方法在一定程度上有着相对的安全性。