Clinical studies were found that a single nucleotide polymorphism influenced response or drug toxicity in cancer chemotherapies,which were based on 5-fluorouracil,Irinotecan,platinum and so on.

• 临床研究发现,以化疗药物氟尿嘧啶、伊立替康、铂类药物等为基础的化疗过程中,由于单核苷酸的多态性,患者出现临床疗效或药物毒性作用不同。