Chiral ligand-exchange chromatography (CLEC) is one of the basic chromatography method for enantiomer separation, in which chiral ligands and metal ions are two essential elements to determine the chiral selectivity.

• 手性配体交换色谱法是分离手性化合物的基本方法之一，其中手性配体和金属离子是决定手性化合物分离选择性的根本因素。