Chickens and rabbits were immunized by purified BVDV and hyperimmune serum whose AGP titer was more than 1:32 and IgY whose ELISA titer was 1:6400of anti-BVDV were prepared, and get development law of its.

• 用纯化BVDV分别免疫家兔和蛋鸡,制备出琼扩效价为1:32以上的兔抗BVDV高免血清与ELISA效价为1:6400的抗BVDV卵黄抗体,并分别得出这两种抗体消长的规律。