Catalyzed by Aluminium trichloride, 3-chloro-l-(2-thienyl)-propanone was prepared through the acylation between thiophene and 3-chloropropinylchloride.

• 本文着重研究了以傅克酰基化为主的合成路线。噻吩和3-氯丙酰氯在氯化铝的催化作用下,发生酰基化反应合成了3-氯-1-(2-噻吩)-丙酮。