CRP induces the production of PAI-1 and quenches the production of PGI2 in ECV304 cells and thus has implications for angiospasm,thrombosis and ACS.

• CRP可直接促进内皮细胞释放PAI-1,抑制PGI2的分泌,从而促使血管痉挛、血栓形成和急性冠脉综合征的发生发展。