CONCLUSIONS: These data suggest that inhibiting the CCL2/CCR2 axis affects brain reperfusion outcome by reducing brain edema, leukocyte infiltration, and inflammatory mediator expression.

• 结论：这些资料显示抑制CCL2/CCR2轴可通过减轻水肿、白细胞浸润和炎性介质表达而影响大脑再灌注预后.