CONCLUSION: Local application of VEGF and bFGF can improve fracture healing.VEGF accelerates early fracture healing, and bFGF improve intermediate and advanced stage of fracture healing.

• 结论：骨折时局部应用内皮细胞生长因子、碱性成纤维细胞生长因子可促进骨折愈合，内皮细胞生长因子促进早期骨折愈合，碱性成纤维细胞生长因子促进中晚期骨折愈合。