CONCLUSION Liver cells were damaged severely in the rats with DEN-induced hepatoma.The liver mass increased without any significant changes in the liver function tests as phenacetin metabolites.

• 结论在DEN诱发肝癌大鼠，肝细胞严重受损，肝脏体积增大，非那西丁代谢等肝功能试验无明显改变。