CONCLUSION In the development of diffuse brain injury with SBI, mGluR3 may play an important role in protecting brain, and its agonist DCG IV can availably alleviate the degree of brain injury.

• 形态学研究证实 ；DCG- IV干预能明显减轻脑皮层神经元损伤程度 .；结论 在弥漫性脑损伤和 SBI所致的脑损害发生与发展过程中；m Glu R3的作用可能与脑保护有关；其激动剂 DCG- IV能有效降低脑组织损伤程度