By ig CADOL 9,15,30g/kg for 60d,the diet,action,growth,hemogram,liver,kidney function and main viscera of rats were not influenced obviously.

• 该口眼液小鼠ig最大耐受剂量为200g/kg，长期毒性试验表明，口服液连续ig60d（9，15，30g/kg·d）对小鼠的饮食，行为活动，生长发育，血象，肝、肾功能及主要脏器无明显影响。